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Snake Alchemist

(3,318 posts)
Sun Feb 12, 2012, 10:34 PM Feb 2012

Deception at Duke - HUGE cancer treatment fraud

Chemotherapy can be a tough road for people with cancer, often debilitating and even dangerous. Which is why five years ago, when Duke University announced that it had an advanced, experimental treatment that would match chemotherapy to a patient's own genetic makeup, it was hailed as the holy grail of cancer care. The scientist behind the discovery was Dr. Anil Potti, and soon Dr. Potti became the face of the future of cancer treatment at Duke, offering patients a better chance even with advanced disease. However, when other scientists set out to verify the results, they found many problems and errors. What our 60 Minutes investigation reveals is that Duke's so-called breakthrough treatment wasn't just a failure -- it may end up being one of the biggest medical research frauds ever.

Five years ago, Duke University announced it had found the holy grail of cancer research. They'd discovered how to match a patient's tumor to the best chemotherapy drug. It was a breakthrough because every person's DNA is unique, so every tumor is different. A drug that kills a tumor in one person, for example, might not work in another. The research was published in the most prestigious medical journals. And more than a hundred desperately ill people invested their last hopes in Duke's innovation.

In 2010, we learned that the new method was a failure. But what isn't widely known, until tonight, is that the discovery wasn't just a failure, it may end up being one of the biggest medical research frauds ever - one that deceived dying patients, the best medical journals and a great university.


http://www.cbsnews.com/8301-18560_162-57376073/deception-at-duke/?tag=contentMain;contentBody

26 replies = new reply since forum marked as read
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Deception at Duke - HUGE cancer treatment fraud (Original Post) Snake Alchemist Feb 2012 OP
This makes me ill Irishonly Feb 2012 #1
So much for the Hippocratic Oath. nt Snake Alchemist Feb 2012 #2
Yep, we're all liars and frauds. The oath means nothing to any of us. elias7 Feb 2012 #19
I think S.A. was referring only to the doctor in the article renate Feb 2012 #20
You read it right. nt Snake Alchemist Feb 2012 #21
My apologies, then. elias7 Feb 2012 #26
Yeah, stereotyping is not a good way to think Yo_Mama Feb 2012 #23
Ditto n/t malaise Feb 2012 #8
Rec for visibility seeviewonder Feb 2012 #3
sad. n/t RainDog Feb 2012 #4
Bastards. More bad publicity for Duke-----what a place. virgogal Feb 2012 #5
This is criminal. riverbendviewgal Feb 2012 #6
Makes you wonder what research is legitimate. nt Snake Alchemist Feb 2012 #7
Follow the money. nanabugg Feb 2012 #9
Just like everywhere else, LisaL Feb 2012 #25
There was a more detailed article about this published in the Economist in 9/2011.. Princess Turandot Feb 2012 #10
Thanks for the additional info. nt Snake Alchemist Feb 2012 #12
kr...nt TeeYiYi Feb 2012 #11
Red wine researcher accused of fraud flexnor Feb 2012 #13
How do you tell a family their last chance was lost to fraud? flexnor Feb 2012 #14
The Medical field has been corrupted and bought lovuian Feb 2012 #15
That's part of it. The other part is that doctors have been made into demi-gods. Snake Alchemist Feb 2012 #17
I lost my mom to cancer LibertyLover Feb 2012 #16
The Dr.'s name was a warning: Dr. Potti rusty fender Feb 2012 #18
I lost my 36 yo sister to throat cancer 20 years ago. I remember the desperation GliderGuider Feb 2012 #22
he now has a private practice (lucrative?) in Snake Alchemist Feb 2012 #24

elias7

(4,037 posts)
19. Yep, we're all liars and frauds. The oath means nothing to any of us.
Mon Feb 13, 2012, 08:31 PM
Feb 2012

One of my ER colleagues sees a medicaid patient, and he launches into that old diatribe about no one pulling their weight anymore, today's youth's sense of entitlement...blah blah blah. He thinks all people on welfare are abusing the system because we tend to see that couple percent that do in fact abuse the system.

"So much for the hippocratic oath" says to me the same thing as declaring all medicaid recipients "Welfare Queens". Or calling all cops abusive assholes because of the OWS violence by some. Or calling all republicans moronic cretins....oh wait, forget that one.

These threads remind me that people have some issues with certain institutions, perhaps rightly so on some levels, but I think it's important to remember that DU has a very big umbrella, and I imagine I am not the only doctor to feel I belong here. At least most of the time.

renate

(13,776 posts)
20. I think S.A. was referring only to the doctor in the article
Mon Feb 13, 2012, 08:40 PM
Feb 2012

and was, by implication, saying that doctors do take the Hippocratic Oath very seriously and that this particular doctor betrayed his profession by violating it.

Admittedly I'm reading a lot into just a few words--but that's how I responded to that post.

elias7

(4,037 posts)
26. My apologies, then.
Mon Feb 13, 2012, 11:33 PM
Feb 2012

I misinterpreted your statements about the worth of the hippocratic oath, the charge of doctors having inflated egos and being made into demi-gods, and the wondering about what research is legitimate. I thought you were generalizing, rather than talking about this specific thing.

I will say, that the days of inflated egos and demi-goddery is really quite over; has been for about 2 decades. That superior attitude is "old school" and those physicians are at retirement age or already retired. I think public perception/consciousness has lagged in this regard.

I would also say, that although physician groups (i.e AMA) are vulnerable to lobbying, most of us are not in anyone's pocket, not beholden to special interests, and really are fairly simple people.

In my residency years, our residency director halted drug company lunches due to the potential for unfair influence. It was unnecessary, though. None of us took these reps seriously. We were data and evidence driven then as now, and wouldn't let a free piece of pizza or a pen convince us to use something that was not appropriate or had weak data to support an indication.

Yo_Mama

(8,303 posts)
23. Yeah, stereotyping is not a good way to think
Mon Feb 13, 2012, 09:31 PM
Feb 2012

I suppose it's human to be vulnerable and to react in anger to a story such as this, but it's still not valid to lump the innocent with the guilty.

riverbendviewgal

(4,254 posts)
6. This is criminal.
Sun Feb 12, 2012, 10:44 PM
Feb 2012

I lost two family members to cancer 10 and 12 years ago. We did a lot of researching and hung on to every ray of hope.

Sounds to me like there should be a big investigation of Dr. Potti and Duke University should face charges.

 

nanabugg

(2,198 posts)
9. Follow the money.
Sun Feb 12, 2012, 10:49 PM
Feb 2012

No doubt he was a big NIH grantee too. So much crap about the grant process in biomedical research, i can't even begin to go into it.

LisaL

(44,982 posts)
25. Just like everywhere else,
Mon Feb 13, 2012, 09:34 PM
Feb 2012

it's not always so easy or quick to figure out if something is fraudulent.

 

flexnor

(392 posts)
13. Red wine researcher accused of fraud
Mon Feb 13, 2012, 01:05 PM
Feb 2012

A University of Connecticut researcher known for his work on red wine's benefits to cardiovascular health falsified his data in more than 100 instances, university officials said Wednesday.

University officials said nearly a dozen scientific journals are being warned of the potential problems after publishing his studies in recent years. The researcher, Dipak Das, did some studies of resveratrol, an ingredient in red wine that has shown potential for promoting health.



Read more: http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2012/01/11/MNIJ1MO400.DTL#ixzz1mHZXnSXD
 

flexnor

(392 posts)
14. How do you tell a family their last chance was lost to fraud?
Mon Feb 13, 2012, 01:12 PM
Feb 2012

'uh,..sorry about that, Chief'

I have known an oncologist a cousin married for a long time. I've always wondered how he told a patient 'that's it', but no doubt that's part of the job

Imagine being the one to tell a family, 'that's it, the doctor is a scammer, how were we supposed to know he wasnt really a rhodes scholar, that could have added 20 minutes to the hiring process'

In IT, I was told to do double verify on resumes/tech screens under certain circumstances, which i will not mention here

 

Snake Alchemist

(3,318 posts)
17. That's part of it. The other part is that doctors have been made into demi-gods.
Mon Feb 13, 2012, 01:45 PM
Feb 2012

Inflated egos are just as much a problem.

 

GliderGuider

(21,088 posts)
22. I lost my 36 yo sister to throat cancer 20 years ago. I remember the desperation
Mon Feb 13, 2012, 09:29 PM
Feb 2012

...as we looked for any treatment that held out a reasonable possibility of helping, and the odds got longer and longer.

These bastards will prey on people like my parents, and in the end give them back their children in a pine box.

I hope they jail the SOB until he dies ... of cancer.

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