who think that there is a simple hormone that will cure homosexuality, read the paper before going off into the twilight zone and claiming the magic elixir is just around the corner.
First in terms of hormones:
http://www.biolreprod.org/cgi/content/abstract/67/1/263<snip>
Relationship of Serum Testosterone Concentrations to Mate Preferences in Rams1
Charles E. Roselli2,a, Fred Stormshakb, John N. Stellflugc, and John A. Reskoa
a Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, Oregon 97201 b Department of Animal Sciences, Oregon State University, Corvallis, Oregon 97331 c United States Sheep Experiment Station, Dubois, Idaho 83423
This study examined systemic testosterone concentrations in rams that were classified according to their sexual behavior and partner preference as either female-oriented (FOR), male-oriented (MOR), or asexual (NOR). For this purpose, we measured testosterone concentrations under three separate conditions: in conscious rams during the nonbreeding season (June) and breeding season (November), and in anesthetized rams during the breeding season. Basal testosterone concentrations in conscious rams were not different among the three groups (P > 0.05) in either season. However, when rams were anesthetized, mean systemic concentrations of testosterone in FORs (mean ± SEM, 13.9 ± 7.4 ng/ml serum) were greater (P < 0.05) than in NORs (0.9 ± 0.1 ng/ml), but not in MORs (2.2 ± 6.2 ng/ml), whereas testosterone concentrations were not different between MORs and NORs (P > 0.05). Concentrations of testosterone in the spermatic vein of FORs (127 ± 66 ng/ml) were greater (P < 0.05) than in MORs (41 ± 10 ng/ml) and NORs (19 ± 7 ng/ml). Serum LH concentrations were not different. Cortisol was higher (P < 0.05) in anesthetized MORs (25.1 ± 4.2 ng/ml) and NORs (27.2 ± 4.4 ng/ml) than in FORs (10.9 ± 1.8 ng/ml). These results demonstrate that circulating testosterone concentrations are related to sexual behavior only when rams are bled under anesthesia. Thus, differences in basal androgen concentrations in adulthood cannot be responsible for expression of male-oriented preferences or low libido in sheep. Instead, functional differences must exist between the brains of rams that differ in sexual preference expression.
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Roselli's work has identified specific neurological changes in the brain, in particular, the hypothalamus, of male oriented male sheep. From a popular (i.e. non-scientific) article summarizing various animal sexuality issues:
http://www.tierramerica.net/2005/0226/iacentos2.shtml<snip>
In the study published in 2004, physiologist Charles Roselli and his team said they discovered groups of brain cells that were different amongst the sheep and that showed a strong correlation with their sexual preference. Roselli dubbed this knot of nerve cells ''ovine sexually dimorphic nucleus, oSDN.
The team examined 27 adult sheep, four years old and of different breeds, raised on an agricultural research station in the northwestern state of Idaho. The sample included eight males who manifested heterosexual behavior, nine with homosexual behavior and 10 females.
The research determined that the oSDN of the males who preferred females was considerably larger and contained many more neurons than in the other 19 sheep.
''Ours and other similar studies strongly suggest that the sexual preference among animals is biologically determined,'' Roselli told a press conference. When he presented the report the physiology and pharmacology professor added, ''This possibility is also valid for humans.''
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Finally, is a pointer to Goggle Scholar with a list of Roselli's work, he is quite well published. The list contains the seminal work referenced by the article:
http://scholar.google.com/scholar?hl=en&lr=&q=charles+roselliLast but not least, PETA is all hot and bothered by research using animals and are targeting Roselli. PETA would put scientific research back 100 years if they could. Fortunately, fewer and fewer people are listening to this animal extremist group anymore.