Reply #2: That doesn't work on rheumatoid arthritis. [View All]

Right now I'm living on Prednisone and Tylenol #3. It's all I can afford. I still have half a prescription of Celebrex left, but thought that it might have something to do with the mild right sided failure and shortness of breath I'd been having, so I stopped it when Vioxx was withdrawn. I'd been on it for 3 years.

It's doubtful that the above described mechanism is the correct one. Preliminary research suggests that COX-1 has a pro clotting effect, and that inhibiting COX-2 allows that effect to continue unchecked. There's also research that shows COX-1 has a role in causing arterial plaque to rupture.

The real problem here is the stupid war on drugs. Opiates are the safest and most effective treatments for chronic pain out there, but there is great pressure on pharmaceutical companies to come up with non narcotic analgesics because of the stupid drug war. They've only succeeded in coming up with dangerous drugs that kill people. Remember Zomax?

I'd advise against taking COX-2 inhibitors if there is any other alternative available until the final word is in on the mechanism that has been killing people.