Before the advent of the "Stains" the only good treatment for high Cholesterol was niacin (Vitamin B-12) for it had the effect of converting LDL ("bad") Cholesterol to HDL (Good) Cholesterol. Niacin is still the only drug the converts bad to good cholesterol (exercise also has the effect of converting Bad to Good Cholesterol).
My point is with the use of Niacin (Or any of its relatives) you will NOT see a drop in any overall Cholesterol count, but you should see a conversion from LDL to HDL Cholesterol. HDL Cholesterol appears to PREVENT heart attacks, while LDL Cholesterol is an indication that you are heading for one.
More on LDL and HDL Cholesterol:
http://www.americanheart.org/presenter.jhtml?identifier=180Now I am on a Niaspan (A Niacin variation), Tricor, Lipitor and Zitia regime. This combination has dropped by Cholesterol count almost 400% (That what you get when you go from 800 Plus to below 200). I have not had an angina attack in over 20 years of being on a "stain" and Niacin,, but understand HOW both the "Stains" work and how Niacin works, the former actually removes Cholesterol, Niacin just converts it from a bad form to a good form.
Tricor and Lipitor are "Stains" that seems to work together and reduces cholesterol (Both work through the liver where removal of Cholesterol appears to occur naturally). Zitia (Which my doctor took me off when my cholesterol count stayed below 200) works in the bowels. When I went on it (and when I went off it) I had a two to three weeks problems with my bowel movement (Tendency to diarrhea). I have NOT had a problem with Lipitor or Tricor, through I do notice if I am off them for a few days my sexual drive picks up). I read one place where their compared Cholesterol with testosterone and both seems to be very closely related (i.e. the high Cholesterol may be the result of some malfunction in testosterone production NOT a problem with the liver). Women tend to be safe when this increase sex drive hits me (I like sex, rape is NOT sex) except if they would have me.... But other then that I have NOT had any problems with Lipitor or Tricor. I have had an ache in my arm (which may be a side affect of Lipitor) but it is minor and recent development.
Now, I also have to watch for "side affects" that are NOT "Side Affects" per se, but my body doing what it is SUPPOSE to do, but given my long history of high Cholesterol I never had before. The classic example of this is hunger pains. I never had them growing up. I never had them even when I did NOT eat for days (I was on a voluntary crash diet, but no "hungry pains"), but after a few years on Lipitor as my cholesterol drop to "Normal" I started to have "hungry pains" after a few hours of not eating i.e. about lunch time, about dinner time. When I was growing up I always ate, but NOT when I was hungry, but when it was time to eat set by others (or by convention, everyone else was eating so I did). Thus I do NOT think these "hungry pains" are a true side affect of Lipitor, but the side affect of my Cholesterol returning to normal levels and my body responding as it should when it needs feed.
Just comments on the "side affects" I have notice while on Lipitor, all controllable. Now, Niacin has a nasty side affect on me, but it occurs rarely and within about an hour of me taking it. Every so often (more often when I take niacin without food, but NOT that much more often) it turns me beat read with a severe rash. It goes away after about 30 minutes (And occurs more often in summer then winter, for I notice when it hits I need to turn on the A/C to "cool down" the rash). I have been on Niaspan for over 20 years and I still get such attacks, but they are rare, almost NEVER in Cold Weather and taking the Niaspan with food seems to minimize the effect.
The above are the only side affect I have notice while on the above medication. The Physician Desk Reference mentioned others but I have never had them hit me (or never realized they were hitting me). Overall I believe I am better off on the medications then off them but that is my view based on my experience with the drugs.