Sit Genome!

Good dog!

http://www.washingtonpost.com/wp-dyn/content/article/2005/12/07/AR2005120702457.html

for our best friends.

but i doubt if there's a gene for why we're so devoted to each other.

dogs rule
everybody else to the back of the room.

It's a given.

p.s. when my big 80 lb husky mix, sport was alive --
he had to do what my neighbor's cat told him to do.
i can say that now that he has gone. he wouldn't let me when he was alive.

I would too. Post a picture, if you're able.

i can barely turn the thing on -- downloading picts is as yet beyond this poor neanderthal.

oh do i miss him -- he was my baby -- the perfect dog for me -- my best friend --
it's been 3 years i think and it's left a hole you could drive a truck through.

p.s. he had a little brother -- a yorkie -- 5 lbs.
peewee -- both dogs were foundlings.

and you were a best friend to him. For that, you've done a wonderful thing. Amazing how pets become so important in our lives, huh?

they're doing this to gain knowledge about human diseases.

Anything they learn about canine health will be secondary to that. Being a dog lover, I agree that that's also a good thing.

Thank you for posting it.

Of course, the whole concept of what they're doing is based on evil-lution so of course it must be a waste of time! :sarcasm:

The kind of knowledge they'll get from this shows the value of having an understanding of natural selection. I wish we could make more people understand that.

mitigate or possibly cure without toxic drugs or radiological means. Not saying that these things don't work, I know they do... but who wants to use them in the first place if there is a way to prevent the need for them from appearing?

http://www.sciencedaily.com/releases/2005/09/050916074339.htm
Prevent Prostate Cancer With Antioxidants? Gene Pathway May Reveal More Clues

Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage. The pathway, which is also involved in human prostate cancer, may help determine how and whether antioxidants, such as certain vitamins or their products that reverse the damage, can prevent prostate cancer.

The researchers, from Johns Hopkins Kimmel Cancer Center and The Cancer Institute of New Jersey, found that when the tumor suppressor gene Nkx3.1 malfunctions, prostate cells lose the ability to protect themselves from oxygen damage. Results of the new studies are in the August issue of the journal Cancer Research.

"Normally, cells with functioning Nkx3.1 seem to process oxidative free radicals appropriately," says Theodore L. DeWeese, M.D., a co-author of the study and director of the Department of Radiation Oncology & Molecular Radiation Sciences at Hopkins. "But cells with faulty Nkx3.1 genes cannot manage oxidative injury. Then, their DNA gets damaged, and that leads to other mutations that in turn can bring about cancer."

The researchers specifically found that a key role of Nkx3.1 is to prevent oxidative damage by regulating the expression of other genes. Oxygen causes cellular degeneration through so-called oxidative free radicals --- highly reactive atoms with an unpaired electron that can rip through cells like a bullet. Free radicals are produced as a result of normal body metabolism, and are widely known to be intimately involved in aging, as well as cancer development.