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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Mar-19-06 04:39 PM
Original message
Studies, clinical exp. demonstrate dental amalgam major cause of MS
Prochazkova J, Sterzl I, Kucerova H, Bartova J, Stejskal VD; The beneficial effect of amalgam replacement on health in patients with autoimmunity. Neuro Endocrinol Lett. 2004 Jun;25(3):211-8.

http://www.nel.edu/pdf_/25_3/NEL250304A07_Prochazkova_.pdf

Results of lymphocyte reactivity measured with MELISA indicate that in vitro reactivity after the replacement of dental amalgam decreased significantly to inorganic mercury, silver, organic mercury and lead. All 6 patients with MS showed significant improvement in health.
Out of 15 patients with systemic lupus erythematosus (SLE) 11 (73%) had improvement of health.
Out of 8 patients with autoimmune thyroiditis 6 showed significant improvement in health (75%). Of the patients that did not have evidence of significant improvement, most tested immune reactive to nickel and the autoimmunity measure was not improved at the end of the study. For those whose condition was worse, the autoimmunity measure for nickel was higher- indicating that amalgam replacement did not resolve the source of nickel exposure.


Huggins HA, Levy,TE, Solving the MS Mystery: Help, hope and recovery, 2002

Hal Huggins replaced the amalgams of over 1000 patients with multiple sclerosis. After amalgam replacement the majority had significant improvement in their condition. Tests conducted on the patients also showed significant improvement in blood parameters and/or cerebrospinal fluid characteristics.

H.A.Huggins & TE Levy, "cerebrospinal fluid protein changes in MS after Dental amalgam removal", Alternative Med Rev, Aug 1998, 3(4):295 300.

A relationship between multiple sclerosis (MS) and dental silver-mercury fillings has been suggested by some investigators, but never proven. This study documents objective biochemical changes following the removal of these fillings along with other dental materials, utilizing a new health care model of multidisciplinary planning and treatment. The dramatic changes in photolabeling of cerebrospinal fluid (CSF) proteins following these dental interventions suggest CSF photolabeling may serve as an objective biomarker for monitoring MS. The clear-cut character of these changes should also encourage more research to better define this possible association between dental mercury and MS.


There are extensive documented cases (more than a thousand) where removal of amalgam fillings led to cure of MS (35c,94,95,102,163,170,212,222,271,291,302,468,470,34,35,229, 406,468,485,523)
references: http://www.home.earthlink.net/~berniew1/ms.html


Mutter J, Daschner F, et al, Amalgam risk assessment with coverage of references up to 2005] , Gesundheitswesen. 2005 Mar;67(3):204-16.
(Medline)
Abstract
Dental Amalgam contributes substantially to human mercury load. Mercury accumulates in some organs, particularly in the brain, where it can bind to protein more tightly than other heavy metals (e. g. lead, cadmium). Therefore, the elimination half time is assumed to be up to 1 - 18 years in the brain and bones. Mercury is assumed to be one of the most toxic non-radioactive elements. There are pointers to show that mercury vapour is more neurotoxic than methyl-mercury in fish. Review of recent literature suggests that mercury from dental amalgam may lead to nephrotoxicity, neurobehavioural changes, autoimmunity, oxidative stress, autism, skin and mucosa alterations or non-specific symptoms and complaints. The development of Alzheimer's disease or multiple sclerosis has also been linked to low-dose mercury exposure. There may be individual genetical or acquired susceptibilities for negative effects from dental amalgam. Mercury levels in the blood, urine or other biomarkers do not reflect the mercury load in critical organs. Some studies regarding dental amalgam reveal substantial methodical flaws. Removal of dental amalgam leads to permanent improvement of various chronic complaints in a relevant number of patients in various trials. Summing up, available data suggests that dental amalgam

Regulation of brain aquaporins. Neuroscience. 2004;129(4):947-55.

Gunnarson E, Zelenina M, Aperia A.

Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden.

Emerging evidence suggests that brain aquaporins (AQP) play important roles for the dynamic regulation of brain water homeostasis and for the regulation of cerebrospinal fluid production. This review deals with the short- and long-term regulation of AQP4 and AQP9, both expressed in astrocytes, and of AQP1, expressed in the choroid plexus. AQP1 and 4 have in other cell types been shown to be regulated by phosphorylation. Phosphorylation affects the gating of AQP4 and the trafficking and insertion into membrane of AQP1. Mercury inhibits the water permeability of AQP1 and AQP9, but not AQP4. The permeability of AQP4 is increased by lead. Further insight into the mechanisms by which brain AQPs are regulated will be of utmost clinical importance, since perturbed water flow via brain AQPs has been implicated in many neurological diseases and since, in brain edema, water flow via AQP4 may have a harmful effect

Brain barrier systems: a new frontier in metal neurotoxicological research. Toxicol Appl Pharmacol. 2003 Oct 1;192(1):1-11.

Zheng W, Aschner M, Ghersi-Egea JF.

School of Health Sciences, Purdue University, West Lafayette, IN 47907, USA. wz18@purdue.edu

The concept of brain barriers or a brain barrier system embraces the blood-brain interface, referred to as the blood-brain barrier, and the blood-cerebrospinal fluid (CSF) interface, referred to as the blood-CSF barrier. These brain barriers protect the CNS against chemical insults, by different complementary mechanisms. Toxic metal molecules can either bypass these mechanisms or be sequestered in and therefore potentially deleterious to brain barriers. Supportive evidence suggests that damage to blood-brain interfaces can lead to chemical-induced neurotoxicities. This review article examines the unique structure, specialization, and function of the brain barrier system, with particular emphasis on its toxicological implications. Typical examples of metal transport and toxicity at the barriers, such as lead (Pb), mercury (Hg), iron (Fe), and manganese (Mn), are discussed in detail with a special focus on the relevance to their toxic neurological consequences.

For documentation of the mechanisms by which mercury causes MS, Lupus, Thyroiditis, etc. see
http://www.home.earthlink.net/~berniew1/ms.html
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IndyOp Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Mar-19-06 05:01 PM
Response to Original message
1. Serious, wow. But how do you define 'cure' --
Edited on Sun Mar-19-06 05:08 PM by IndyOp
Reading just the abstracts above, it seems really clear that there is improvement, but I am hesitant about this: "There are extensive documented cases (more than a thousand) where removal of amalgam fillings led to cure of MS."

I am not being critical, just appropriately skeptical...

On edit: I followed your link to find "There are extensive documented cases (many thousands) where removal of amalgam fillings led to cure of serious health problems such as MS..., ALS..., Parkinson’s/ muscle tremor..., Alzheimer’s’s..., Chronic Fatigue Syndrome..., muscular/joint pain/Fibromyalgia..., depression.... In several of the studies, over 75% of those with MS and having amalgams replaced recovered or had significant improvement( 212(a),(b),(e),302,222,35). Some of the studies reported similar success rates for SLE but with lower number of cases treated."

In several studies, over 75% recovered or had significant improvement =/= CURED.

I *love* the potential of alternative medicine and wish to heck I could teach people who are doing research or writing about the results of such research to *tone down* their claims -- it would increase their credibility.
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 02:17 PM
Response to Reply #1
11. I agree
If I had ms, this would be enough proof for me to get my amalgams safely removed, and hope for the best. As it is my amalgams are staying put.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Sun Mar-19-06 08:06 PM
Response to Original message
2. philb, I agree with IndyOp.
In several studies over 75% recovered or had significant improvement, but that does not equal CURED.

As you probably know from my posts, I also *love* the potential of alternative medicine and I also wish to heck people who write up the findings would *tone down* their claims -- it would increase their credibility.

Here is an example - your 1st study (a PDF)in this OP actually reads:

The beneicial effect of amalgam replacement on health in patients with autoimmunity


Jarmila Prochazkova , Ivan Sterzl , Hana Kucerova , Jirina Bartova & Vera DM Stejskal

The Institute of Dental Research 1st Medical Faculty Charles University and General University Hospital, Prague,
CZECH REPUBLIC

The Institute of Endocrinology, Prague, CZECH REPUBLIC MELISA MEDICA FOUNDATION, Stockholm, SWEDEN Associate Professor of Immunology, University of Stockholm, SWEDEN Correspondence to:
Jarmila Prochazkova, M.D., Ph.D.,
The Institute of Dental Research 1st
Medical Faculty CU and GUH,
Vinohradská 48, 120 21 Prague, Czech Republic
TEL: +420224256718;
FAX: +420224247034
EMAIL: prochazkova@vus.cz

Submitted: March 9, 2004
Accepted: April 16, 2004

ABSTRACT

BACKGROUND:
Patients with certain autoimmune and allergic diseases, such as systemic lupus, multiple sclerosis, autoimmune thyroiditis or atopic eczema, often show increased lymphocyte stimulation by low doses of inorganic mercury in vitro. The patients often report clinical metal hypersensitivity, especially to nickel.

OBJECTIVE AND METHODS:
In this study we examined the health impact of amalgam replacement in mercury-allergic patients with autoimmunity. The suitability of MELISA®, an optimized lymphocyte stimulation test, for the selection of susceptible patients and monitoring of sensitization was also examined. Amalgam illings were replaced with composites and ceramic materials. Followup health status and lymphocyte reactivity were assessed and evaluated half a year or later following amalgam removal.

RESULTS:
Results of lymphocyte reactivity measured with MELISA® indicate that in vitro reactivity after the replacement of dental amalgam decreased significantly to inorganic mercury, silver, organic mercury and lead. Out of 35 patients, 25 patients (71%) showed improvement of health. The remaining patients exhibited either unchanged health (6 patients, 17%) or worsening of symptoms (4 patients, 11%). The highest rate of improvement was observed in patients with multiple sclerosis, the lowest rate was noted in patients with eczema. The initial mercury-speciic lymphocyte reactivity was signiicantly higher in the responder group, than in the non-responders, whose health was not improved by amalgam removal. All patients with health improvement after amalgam replacement showed reduced proliferation to inorganic mercury in follow-up MELISA®. In vitro responses to phenylmercury and nickel did not differ between the groups.

CONCLUSIONS:
Mercury-containing amalgam may be an important risk factor for patients with autoimmune diseases. MELISA® is a valuable tool for selection of patients for amalgam replacement and also for monitoring of metal allergies.



When I read the conclusion, here is how it strikes me:

CONCLUSIONS:
Mercury-containing amalgam may be an important risk factor for patients with autoimmune diseases. MELISA® is a valuable tool for selection of patients for amalgam replacement and also for monitoring of metal allergies.

OK, the word "may" means that it is suspected by the authors but not proven. The phrase "may be an important risk factor" may (or may not) be an important piece of the puzzle but it's a huge stretch to call it a cause or a cure. On the other hand, it does spark my interest to look further.


I think that any study should be capable of standing on it's own. When one, shall we say "enhances" the author's findings, it opens you up to being flamed and any value that the study may have had simply goes down in flames with you.

I hope you do not take offense at my comments, it's just my 2 cents.

One more thing, I use a simple little inexpensive program called Foxit PDF Editor for manipulating PDFs http://www.foxitsoftware.com/pdf/pe_intro.php.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Mar-19-06 10:52 PM
Response to Reply #2
3. A lot of them were "cured" as in as healthy as others in their age group,
some only significantly improved. It depends on the case, how much nerve damage had been done before treatment started,
how rigorously the patient pursued the treatment, and the expertise of the treating clinics.

I think its pretty clear that these aren't really "diseases", but rather symptoms caused by exposure to neurotoxics and immunotoxics.
The disease is defined by the symptoms. Its not something you can catch.

But I have 10 years personal experience interacting with the patients and clinics treating such conditions, both in the U.S. and
otherwise. And I personally know a lot of those. Two people in my family, including me, have recovered from chronic diagnosed
mercury toxicity/lupus/chronic fatigue/Fuch's Disease/etc. etc. And most of the DAMS coordinators whom I interact with,
and thousands of patients myself and other DAMS coordinators have interacted with. We have a lot of the names and contact info, plus clinic contacts, plus info on a lot of test results, etc.; plus the documentation on 60,000 cases of recovery from chronic conditions- much of it by peer-reviewed studies: http://www.home.earthlink.net/~berniew1/hgremove.html

I could provide a lot of testimonial type info that I haven't regarding recoveries, it seems that doing so is discouraged by the medical establishment- but I have it available.

I'm usually careful to note we are talking about cured or significant improvement, as you can see from my articles.


similar for other neurological conditions like Alzheimer's, Parkinson's, etc. The mechanisms by which mercury and toxic metals cause these conditions are documented in the medical literature, and there are a lot of cases of cure or significant improvement after proper treatment. Mostly significant improvement for these if they've had significant damage before treatment.
But I personally know people who've recovered or significantly improved from these as well, partially due to my interaction in suggesting tests and clincics, etc.
And its easy to avoid such conditions, since the main causes are known.
http://www.home.earthlink.net/~berniew1/indexa.html
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Sun Mar-19-06 11:25 PM
Response to Reply #3
5. Actually I find personal testimonial interesting. But, it's important...
to clearly state it as such and keep it completely separate from your scientific studies, if you wish to be taken seriously.

With regard to your studies, the fact that "X"% improved by "Y" amount is very important news! Nothing needs to be added to that. It's big news as is.

To extrapolate that this scientifically equates to a "cause" or a "cure" is clearly going to far and ends up detracting from the science that the study attempts to offer.

If you actually have scientific proof I would love to see it. However, I warn you, if you do a large data dumb, or if it's long and hard to read, I will not read it. Take the time to summarize, highlight and format it so it can be read easily and quickly and provide links.

I know that this is a personal issue for you. I respect that. But, if you continue to mix or confuse your personal experience with your scientific studies no one will respect it.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Mar-19-06 11:12 PM
Response to Reply #2
4. the language used in such studies is fairly standard; if they only
Edited on Sun Mar-19-06 11:23 PM by philb
had 35 cases as in this study, they are required to use the language you note to be published in a peer-reviewed journal.
Its not that they doubt the validity of their study. See the www.melisa.org web site for a lot of other such documentation
and my web site for a lot of other supporting documentation.

But in this case, all patients with MS had significant improvement after amalgam replacement. And most for lupus or thyroiditis.
And the few who didn't significantly improve, had known autoimmune causes documented(nickel) that the amalgam replacement did not
get rid off. But based on my experience with such, I think its likely that some of these few will also experience considerable improvement in the future, through figuring out what the source of the nickel that hasn't been dealt with is, or because the
immune system has less burden and over time is better able to deal with the other problems.

But also note that other clinics have had similar experience, one having over 1000 cases of MS improved. And documenting the mechanism involved in a peer-reviewed study.

But another factor that makes a difference in the extent of recovery is nutrition/supplementation- which is documented in the
medical literature to be an important factor in the extent of damage from neurotoxic and immunotoxic exposures, and likewise with regards recovery extent.
http://www.home.earthlink.net/~berniew1/suscept.html for example

and lots more in some of my longer reviews.

thanks for the advice on software, between full time at work and being coordinator of a national org, I need a programmer or secretary to help me with such. Even though I have another family member who's also into this a bit. DAMS has an executive director, who probably knows more about such but he's in another state.
I'm non-paid and spend a huge amount of time on research, probably not enough on software type things that would save me a lot of time and improve output.

These are not the only autoimmune conditions that mercury is often a cause of, as noted in my other papers and posts there are several such. One that there is no dispute about among doctors, dentists, medical schools, dental schools is oral lichen planus- which is a fairly common systemic autoimmune condition known to be caused by dental amalgam and that almost always is "cured" by amalgam replacement. http://www.home.earthlink.net/~berniew1/periodon.html

http://www.home.earthlink.net/~berniew1/immunere.html other conditions
http://www.home.earthlink.net/~berniew1/inflamhg.html
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Sun Mar-19-06 11:33 PM
Response to Reply #4
6. I read your post and I will look at your links when I have more time.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 08:44 AM
Response to Reply #4
7. I have some questions. Brief, to the point answers please.
You wrote:
the language used in such studies is fairly standard; if they only had 35 cases as in this study, they are required to use the language you note to be published in a peer-reviewed journal.

1) For clarity, please quote the language you are reffering to here.
2) What do you mean by "...they are required to use the language you note to be published..."?


3) Please provide a link to your web site

4) Who's web site am I going to when I use these links?
http://www.home.earthlink.net/~berniew1/suscept.html
http://www.home.earthlink.net/~berniew1/periodon.html
http://www.home.earthlink.net/~berniew1/immunere.html
http://www.home.earthlink.net/~berniew1/inflamhg.html

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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 12:17 PM
Response to Reply #4
10. Post hoc - philb, please take a look at this.

Post hoc, also known as "coincidental correlation" or "false cause", is a logical fallacy which assumes or asserts that if one event happens after another, then the first must be the cause of the second.

Post hoc is an example of affirming the consequent. It can be expressed as follows:

* Event A occurred before event B.
* Therefore, A must have caused B.

Example:

1. A rooster always crows prior to sunrise
2. Therefore: the rooster's crowing causes the sun to rise.

Wikipedia®: http://en.wikipedia.org/wiki/Post-hoc_fallacy



In my opinion, post hoc observation can result in strong observational evidence provided that it is put into logical context and especially when it is supported by additional independent evidence.

However, post hoc evidence by itself clearly does not constitute "scientific proof", i.e. the rooster's crowing did not cause the sun to rise!
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Mar-22-06 12:44 AM
Response to Reply #10
35. I've taught logic in college. I fully understand all such.
There is nothing wrong with anything I've posted regarding logic. My major professor was one of the most prestegious in the U.S. in his field of research as well as in study methodology, which I've had a lot of training in and also done consulting
helping others regarding methology with papers that they were writing.
I also have taught statistics in college, and fully understand all aspects of statistics, correlation, logic, etc.

Your example has nothing to do with my review papers, totally different circumstances.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Tue Mar-21-06 09:29 AM
Response to Reply #4
33. Come back philb! You have a right to post here. I didn't mean...
to run you off. You don't have to answer my questions.

If you do choose to follow some of the suggestions that I and many others have offered, I think you'll feel less heat with your posts. It's entirely up to you.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Mar-22-06 12:50 AM
Response to Reply #33
36. I have a life other than DU. I only get here occasionally.
It should be obvious that I spend a lot of time doing research, but I'm also an expert witness that keeps me busy, have a family, serve on lots of advisory committees, interact with thousands with chronic health conditions and clinics treating them each year, etc. I've spent more time here lately than I should, usually late when I should be in bed, like now.
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FM Arouet666 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 12:57 AM
Response to Reply #36
46. I hope you come back more often.
I spend too much time here myself. I have been out of job for several years. Wished I had continued with high school, dropped out after the fourth grade. I spend most of my day playing Nintendo and posting to DU. I almost got a job yesterday, but McDonalds wanted a high school graduate. Damn biased assholes. Anyway, I will continue to monitor the Health forum, seems like an interesting topic.

Argumentum ad verecundiam. Present yourself as an authority, then base your argument upon your self defined credentials. You are certainly an interesting fellow.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 09:36 AM
Response to Original message
8. Please let me know when the Multiple Sclerosis Society...
...accepts your explanation for the cause of the disease, won't you?

http://www.nationalmssociety.org/Sourcebook-Heavy%20Metals.asp

While the cause of MS remains unknown, there is no evidence that heavy metal poisoning is responsible. There have been some claims that mercury leaking from amalgam dental fillings damages the immune system, and causes a broad range of diseases, including MS, by contributing to the demyelinating process. A demyelination process destroys the myelin sheath that surrounds and protects nerve fibers.

There is no scientific evidence to connect the development of MS with dental fillings containing mercury. Although poisoning with heavy metals—such as mercury, lead, or manganese—can damage the nervous system and produce symptoms such as tremor and weakness, the damage is inflicted in a different way and the course of the disorder is also different.


Oh, and one more thing:

Hal Huggins is a proven liar, quack, fraud, and thief.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 09:48 AM
Response to Reply #8
9. philb, trotsky makes an excellent point here.
Your studies were published between 2002 and 2005. That is more than enough time for the MS Society to have discovered them.
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 05:46 PM
Response to Reply #9
12. seems to me the ms society
Should fund some studies on this and put the matter to rest. They obviously don't think that this study constitutes scientific proof. That's fine, but it sure begs for further studies, at the least. I don't need absolute proof to make decisions. If I had MS, I would get my amalgams taken out by an dentist experienced in doing it. Since I don't they are staying in.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 06:13 PM
Response to Reply #12
14. I would love to get to the bottom of this. Like you, based on...
what I've read, if I had MS, I would get my amalgams taken out as well. But I can afford to do that experiment on myself, plus I'm an informed patient.

By some strange coincidence, I happen to know 4 people with MS. Three are women. Their relationships and incomes have been drastically and negatively affected by this disease. I would love to know how to advise them. They know little about this issue and their funds are pretty limited. I am not at all sure what to say.

Scientific proof is not often easily. Calling something scientific proof that isn't only confuses and delays the issue. "...it sure begs for further studies..." Yes, I agree.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 07:59 PM
Response to Reply #12
17. The MS Society has limited funding the way it is.
They can't afford to fund research into an area which hasn't even shown the hint of promise. Far better to direct the money to treatments that have encouraging results and help those with MS live fuller lives in the meantime.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 08:29 PM
Response to Reply #17
18. Actually, "The Society spends more money on MS research than...
any other non-government agency in the world, investing over $35 million annually on research programs...By the end of FY 2006, the Society will have spent over $500 million on research programs."

From: http://www.nationalmssociety.org/Research-FAQFunding.asp
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 09:13 PM
Response to Reply #18
20. Wow, then the fact they don't spend it on amalgam research...
says even more.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 09:18 PM
Response to Reply #20
21. Have a nice evening trotsky.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 09:32 PM
Response to Reply #21
23. Knock off the passive-aggressive crap.
As is the case with most disease/condition societies, I figured they were pressed for funding, and that's why they couldn't spend money researching just anything. According to your link, they have quite a bit of money to spend. Since there is money to go around, the fact that they still choose not to invest in the amalgam angle reveals even more about the legitimacy they feel the area has, doesn't it? Do you think differently, or do you just want to post a snarky "goodbye"?
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 09:48 PM
Response to Reply #23
24. You figured? You figured? See #42
http://www.democraticunderground.com/discuss/duboard.php?az=view_all&address=222x4710#5119

I like you trotsky. It doesn't matter if we disagree. But sometimes you're just too much!
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Tue Mar-21-06 01:27 AM
Response to Reply #23
26. See posts #19 & #25 for an MS Society funded vaccination study.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Mar-21-06 08:17 AM
Response to Reply #26
27. Which only makes my question even more glaring:
if they fund a vaccination study, what does it say about merits of the proposed amalgam link?
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Tue Mar-21-06 09:18 AM
Response to Reply #27
31. OK, you made your point!
Thanks for doing it politely.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Mar-21-06 09:22 AM
Response to Reply #31
32. Subtlety ain't my bag, baby.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 12:14 AM
Response to Reply #20
43. The past President of the Organization says its clear that mercury
is a common cause, and that the organization is controlled by Special Interest money.
Only investigates what is politically correct to investigate; thus gets wrong answers.

Why haven't they come up with a cure? after spending huge amounts of money.
Are you suggesting that they have a better treatment than testing for what is causing the patients
autoimmune condition and treating it.

They don't. As I've noted there are 3 doctors in my immediate extended family and all say the Society has no clue.
One is a neurologist.

Its a matter of record that over a thousand have been cured by metals detox, or had significant improvement,
elimination of disease condition. Stopped progression.

What other treatment are you suggesting is a better option?


All my friends and acquaintances who had MS have gotten cured or stopped progression of condition at a minimum. I've posted a few names of my fellow DAMS coordinators, and have others I could.

Similar for lupus and other autoimmune conditions. I doubt those I interact with are much different than
any other group with those conditions.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 12:11 PM
Response to Reply #43
52. More of the same, philb.
Bash and bash and dismiss anyone who disagrees with you ("no clue"), and trumpet your flawed studies as the only real proof.

Sad.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Mar-22-06 01:19 AM
Response to Reply #8
38. What you say isn't true. Huggins is not only an excellent dentist- but
also has a MS in toxicology and writes peer-reviewed studies in that field as well.
Huggins is one of the most respected dentists in the world. Likely if there was a survey of everyone in the world,
Huggins would come out on top as the most respected dentist in the world.

The only thing Huggins did wrong was cure a lot of people of conditions like MS. He got in trouble with the establishment because apparently dentists are either not supposed to cure people of chronic conditions since they aren't MDs.
Huggins treated over 1000 patients with MS by amalgam replacement, and the majority were "cured" or had significant improvement.
Huggins HA, Levy,TE, Solving the MS Mystery: Help, hope and recovery, 2002 (his book about his MS patients)


But in fact, most people who are cured of chronic degenerative conditions are cured by other than MDs, mostly by dentists
as is well documented in the medical literature. http://www.home.earthlink.net/~berniew1/hgremove.html

Most people with autoimmune conditions like MS that are mostly caused by autoimmunity to mercury or nickel who are cured are mostly cured by amalgam replacement or nickel avoidance.


As I've demonstrated, autoimmunity is one mechanism by which mercury commonly causes chronic conditions-
http://www.home.earthlink.net/~berniew1/immunere.html

But its not the only mechanism by which mercury commonly causes chronic conditions, its documented in the medical literature
that mercury damages and blocks all metabolic enzymatic processes in all organs of the body at extremely low levels of
exposure. This has been documented by studies, as well as millions of tests by medical labs. As I've demonstrated in other threads, supplying cites, and lab data, etc.
But the mechanisms are well known to most researchers and fully documented in the medical literature by thousands of peer reviewed studies, http://www.home.earthlink.net/~berniew1/indexa.html

and the fact that most with many of these conditons recover or have significant improvement after amalgam replacement is
also documented in the medical literature:
http://www.home.earthlink.net/~berniew1/hgremove.html
http://www.home.earthlink.net/~berniew1/hgrecovp.html

People who have no experience regarding mercury research, tests, treatment, etc. saying it ain't so, don't change things.
The case is solidly documented by thousands of studies, and millions of medical lab tests. And the case will only get stronger, my 10 years of personal experience with patients and the clinics treating them make it clear. There is no chance that mercury hasn't been responsible for major effects to millions, and will continue to be so until major changes are made.
The case is now so strong, I think the U.S. will have major restrictions on amalgam and start phasing out amalgam in less than 2 years. Most countries that aren't controlled by special interests already are in the process, and likewise for several states in the U.S. that now require warnings to patients when dentists choose to use mercury/amalgam.

But the case is also made by the significant adverse health effects that have been documented to be common in dentists and dental staff due to occupational exposure to mercury from amalgam.
http://www.home.earthlink.net/~berniew1/dental.html

and the high levels of exposure that sewer plants and sewer sludge and water bodies and fish and the atmosphere are getting from dental amalgam, documented by municipal sewer agencies and ORNL and EPA to be the largest source of mercury in sewers,
and affecting everyone in a significant manner through dental amalgams environmental effects.
http://www.flcv.com/damspr2f.html

The science supports everything I've said. I still haven't seen any evidence provided to the contrary.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Mar-22-06 08:34 AM
Response to Reply #38
39. Hal Huggins was stripped of his license for unethical practices.
He's a fraud and an organization of his peers agrees with me.

The only thing Huggins did wrong was cure a lot of people of conditions like MS.

That is one hundred percent false. Why would the MS Society sit on a cure rather than promote it? Are you saying that the MS Society is WRONG? That they're "in" on the conspiracy to keep Americans suffering? Do they all own stock in mercury?

Huggins treated over 1000 patients with MS by amalgam replacement, and the majority were "cured" or had significant improvement.

Why do you have to put "cured" in quotation marks?

The case is now so strong, I think the U.S. will have major restrictions on amalgam and start phasing out amalgam in less than 2 years.

So in two years when this doesn't happen, will you end your little quest? I'll be saving this post and if we're still around in two years, it should be interesting to see how you spin it then.

The science supports everything I've said. I still haven't seen any evidence provided to the contrary.

Yes, because you refuse to even look at anything that disagrees with you. That has been conclusively demonstrated.
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Warpy Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 06:02 PM
Response to Original message
13. Quackery alert
Canadian quackwatch clearinghouse: http://www.healthwatcher.net/Quackerywatch/MS/index.html

Counterblaste to amalgam quackery: http://skeptically.org/quackery/id23.html

And of course, our old friends at quackwatch weigh in: http://www.quackwatch.org/01QuackeryRelatedTopics/ms.html and they include a whole list of debunking websites: http://www.msakc.org/Articles/MercuryAmalgamFillings.htm

Personally, I feel if you can afford composite fillings, do go for them. They're much more attractive than having a mouthful of blackening amalgam fillings. However, to suggest dental fillings as a cause of multiple sclerosis and their removal as a cure is dangerous and irresponsible.
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 06:25 PM
Response to Reply #13
15. not into all the skeptical websites
Some of my favorite techniques are featured on them!! I am a HUGE NAET fan, totally into it, think it is amazing, and of course they think it is quackery. So, yawn, I don't think much of *that* opinion. LOL. They are a good reference for things to consider trying, though. It seems only the most popular of the outlandish techniques draw their attention. Popularity often (but not always of course) means that they just might be effective!! Naturally I agree with them about some things. Still, they report the evidence they want and ignore the others. Some issues in the past I have gone through with a fine tooth comb, looking up abstracts, comparing rhetoric, etc. They might give a brief nod to an opposing study, and then try to debunk it, if they don't ignore it altogether. Let's just say I am very skeptical about the skeptical websites..

I could probably muster the cost of new fillings, but if their removal is dangerous why should I go for them just for cosmetic reasons? Anyway, I don't open my mouth wide enough for people to notice. For MS naturally I would try NAET and NAET type techniques first. Sorry I know they sound preposterous but my family has truly had amazing experiences with those energetic techniques (and so have other patients I know). No scientific proof that it works of course but I just really don't care (AT ALL) as long as it helps me.
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 07:52 PM
Response to Reply #13
16. Nice links, Warpy.
It's damn near impossible to find truth out there on the Internets. The quack crowd floods the search engines with endless self-referential garbage, trapping far too many people into their lies.
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beam me up scottie Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Mar-20-06 09:21 PM
Response to Reply #13
22. Not into the truth, Warpy.
Edited on Mon Mar-20-06 09:22 PM by beam me up scottie
:evilgrin:
trotsky's right, it does take a while to wade through all the psychobabble from the quacks, pseudo scientists and self proclaimed medical experts, but the truth is out there if people want to find it.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Mon Mar-20-06 08:53 PM
Response to Original message
19. Here's something interesting...

People who are vaccinated against hepatitis B are at increased risk of multiple sclerosis, a study shows.


BBC News 14 September, 2004

US public health experts found the link when they looked at data on more than 1,500 UK patients. The Harvard team does not know whether the vaccine causes MS in those prone to the disease or speeds up MS in those destined to have it. The benefits of protecting against hepatitis might outweigh any risk, wrote the authors in Neurology.

In the latest study Dr Miguel Hernàn and colleagues looked at people registered with a GP in the UK who had been diagnosed with MS between 1993 and 2000. When they looked at hepatitis B immunisation patterns among these 163 MS patients and 1,604 'control' patients without MS from the same GP database, they found a link between the vaccine and MS.

Dr Hernàn said: "We estimated that immunisation against hepatitis B was associated with a three-fold increase in the incidence of MS within three years following vaccination." He said more research would be needed to find out why this might be.

A spokesman for the Multiple Sclerosis Society said: "We need to study these findings in the context of other recent research which has shown no link between the vaccination and MS.

http://news.bbc.co.uk/2/hi/health/3651782.stm
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Tue Mar-21-06 01:23 AM
Response to Reply #19
25. Here is the study - Funded by the MS Society

Recombinant hepatitis B vaccine and the risk of multiple sclerosis A prospective study
Miguel A. Hernán, MD, Dr PH; Susan S. Jick, DSc; Michael J. Olek, DO; and Hershel Jick, MD


Funded by the National Multiple Sclerosis Society (RG3236A1/1).

Abstract—

Background:
A potential link between the recombinant hepatitis B vaccine and an increased risk of multiple sclerosis (MS) has been evaluated in several studies, but some of them have substantial methodologic limitations.

Methods:
The authors conducted a nested case-control study within the General Practice Research Database (GPRD) in the United Kingdom. The authors identified patients who had a first MS diagnosis recorded in the GPRD between January 1993 and December 2000. Cases were patients with a diagnosis of MS confirmed through examination of medical records, and with at least 3 years of continuous recording in the GPRD before their date of first symptoms (index date). Up to 10 controls per case were randomly selected, matched on age, sex, practice, and date of joining the practice. Information on receipt of immunizations was obtained from the computer records.

Results:
The analyses include 163 cases of MS and 1,604 controls. The OR of MS for vaccination within 3 years before the index date compared to no vaccination was 3.1 (95% CI 1.5, 6.3). No increased risk of MS was associated with tetanus and influenza vaccinations.

Conclusions:
These findings are consistent with the hypothesis that immunization with the recombinant hepatitis B vaccine is associated with an increased risk of MS, and challenge the idea that the relation between hepatitis B vaccination and risk of MS is well understood.

NEUROLOGY 2004;63:838–842

PDF: http://www.direct-ms.org/pdf/CausalSpecific/HepatitisBVaccineMS.pdf
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Mar-21-06 08:21 AM
Response to Reply #19
28. Very interesting, especially since Hep-B is mercury-free.
http://www.vaccinesafety.edu/thi-table.htm

Thankfully the MS Society is governed by sensible folks:

A spokesman for the Multiple Sclerosis Society said: "We need to study these findings in the context of other recent research which has shown no link between the vaccination and MS.

"Even on this evidence, however, it is obvious that the serious risks of hepatitis B vastly outweigh any very small possible risk from vaccination."

The MS Trust agreed, saying: "On the basis of this study, one wouldn't want policy as regards to vaccine, to be changed, particularly with such a lethal disease."
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Tue Mar-21-06 09:10 AM
Response to Reply #28
29. "...especially since Hep-B is mercury-free." Yes, I agree.
So far, much has been suspected and little has been proven with this disease.

Here is a study that was productive for a change. I am surprised that they seem so unconcerned at a 310% increase in risk and wouldn't they want to follow this up? What's in this vaccine that is causing this increased risk? Or is this a flawed study?
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Mar-21-06 09:14 AM
Response to Reply #29
30. It's just one study, compared with others that show no link.
So it could be an outlier. The BBC article mentions some other reasons why the correlation may have appeared. Hard to say.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Mar-22-06 12:37 AM
Response to Original message
34. 3 DAMS coordinators who had signif. improvement after amalgam replacement


Multiple Sclerosis and metal allergy: three letters of significant improvement after amalgam replacement.

The following letters were all printed by the US House of Representatives in
its study into mercury, led by Congressman Dan Burton. The 801-page document
was entitled "Mercury in Medicine - are we taking unnecessary risks" and
published in July 2000. Extracts are available online.

http://www.allmassagetherapy.com/177723-MS--Amalgams.html

These are among dozens I personally have interacted with
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Wed Mar-22-06 12:55 AM
Response to Reply #34
37. Interesting, it makes me wonder if some cases of MS...
are actually mercury toxicity. If you recall I posted something that suggested that some people have poor natural mercury elimination and I've read that others seem to be more sensitive to it than others.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 12:39 AM
Response to Reply #37
45. If you read my review articles or those of the clinics that I've posted
that is exactly what I've been saying and what the medical studies and many researchers have been pointing out
for a long time. You are right.
The effects of mercury are not directly dose response; that has been a matter of record in the medical literature for decades.
Some just don't pay attention, I think for some its intentional- how can well documented information in Medline be ignored for years?

As I've noted, the factors that make people susceptable include immune reactivity(which is testable)
Blood allele type (APOE) type 4s can't excrete mercury(and other toxic metals) and accumulate and get very ill over time
in some cases not very much time.

Toxic prenatal exposures damage the fetus detox systems, and destabilize the metallothionein mechanism for metals detox.
Most with autism, ADHD, etc. have been documented to have this condition; and to accumulate mercury and other toxic metals'
which wipes out their neurological and immune systems. this is documented in the medical literature and by many thousands of clinical cases at the Pfieffer Clinic and other autism treatment centers(see URLs on autism thread)

And other susceptibility factors are also likewise documented in the medical literature.
http://www.home.earthlink.net/~berniew1/suscept.html
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Thu Mar-23-06 09:52 AM
Response to Reply #45
48.  Medline: ApoE4 allele, Selenium Status & Prenatal Exposure

Alzheimer disease: mercury as pathogenetic factor and apolipoprotein E as a moderator.


Neuro Endocrinol Lett. 2004 Oct;25(5):331-9.
Mutter J, Naumann J, Sadaghiani C, Schneider R, Walach H.

Institute for Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Germany. jmutter@iuk3.ukl.uni-freiburg.de

The etiology of most cases of Alzheimer's disease (AD) is as yet unknown. Epidemiological studies suggest that environmental factors may be involved beside genetic risk factors. Some studies have shown higher mercury concentrations in brains of deceased and in blood of living patients with Alzheimer's disease. Experimental studies have found that even smallest amounts of mercury but no other metals in low concentrations were able to cause all nerve cell changes, which are typical for Alzheimer's disease. The most important genetic risk factor for sporadic Alzheimer's disease is the presence of the apolipoprotein Ee4 allele whereas the apolipoprotein Ee2 allele reduces the risk of developing Alzheimer's disease. Some investigators have suggested that apolipoprotein Ee4 has a reduced ability to bind metals like mercury and therefore explain the higher risk for Alzheimer's disease. Therapeutic approaches embrace pharmaceuticals which bind metals in the brain of patients with Alzheimer's disease. In sum, both the findings from epidemiological and demographical studies, the frequency of amalgam application in industrialized countries, clinical studies, experimental studies and the dental state of AD patients in comparison to controls suggest a decisive role for inorganic mercury in the etiology of AD.

Publication Types:
Review

PMID: 15580166

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15580166&query_hl=15&itool=pubmed_docsum




Selenium status may also play a role:

The roles of serum selenium and selenoproteins on mercury toxicity in environmental and occupational exposure.


Environ Health Perspect. 2006 Feb;114(2):297-301.

Chen C, Yu H, Zhao J, Li B, Qu L, Liu S, Zhang P, Chai Z.

Laboratory of Nuclear Analytical Techniques and Laboratory for Nanoscale Materials and Related Bio-Environmental Sciences, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, People's Republic of China. chunying.chen@mail.ihep.ac.cn

Many studies have found that mercury (Hg) exposure is associated with selenium (Se) accumulation in vivo. However, human studies are limited. To study the interaction between Se and Hg, we investigated the total Se and Hg concentrations in body fluids and serum Se-containing proteins in individuals exposed to high concentrations of Hg. Our objective was to elucidate the possible roles of serum Se and selenoproteins in transporting and binding Hg in human populations. We collected data from 72 subjects: 35 had very low Hg exposure as evidenced by mean Hg concentrations of 0.91 and 1.25 ng/mL measured in serum and urine, respectively; 37 had high exposure (mean Hg concentrations of 38.5 and 86.8 ng/mL measured in serum and urine, respectively). An association between Se and Hg was found in urine (r = 0.625; p < 0.001) but not in serum. Hg exposure may affect Se concentrations and selenoprotein distribution in human serum. Expression of both selenoprotein P and glutathione peroxidase (GSH-Px) was greatly increased in Hg miners. These increases were accompanied by elevated Se concentrations in serum. In addition, selenoprotein P bound more Hg at higher Hg exposure concentrations. Biochemical observations revealed that both GSH-Px activity and malondialdehyde concentrations increased in serum of the Hg-exposed group. This study aids in the understanding of the interaction between Se and Hg. Selenoproteins play two important roles in protecting against Hg toxicity. First, they may bind more Hg through their highly reactive selenol group, and second, their antioxidative properties help eliminate the reactive oxygen species induced by Hg in vivo.

PMID: 16451871

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16451871&query_hl=3&itool=pubmed_docsum




Early (in uterus and infant) exposure to mercury and lead.



Clin Nutr. 2005 Nov 21; Related Articles, Links

Dorea JG, Donangelo CM.

Laboratorio de Bioquimica Nutricional, Departamento de Nutricao, Universidade de Brasilia, C.P. 04322, 70919.970 Brasilia, Brazil.

Mercury and lead are toxic metals widely spread in the environment with bioaccumulative features that raises public health concerns. Both metals are equally dispersed in the human food chain but exposure and risk of toxicity during early human development are modulated by the diet and nutritional status. Understanding how Hg and Pb occur and interact with nutrients is fundamental to establish guidelines for diminishing exposure and the risk of toxicity. The risk of fetal and infant exposure to Hg can be influenced by maternal amalgam filling (inorganic Hg) and fish consumption (monomethyl Hg), whereas the risk of exposure to Pb is complex: maternal absorption depends on nutrient interactions (Ca and P); and maternal body Pb accumulation responds to all factors known to interact with bone and calcium metabolism. Maternal exposure to Hg and Pb is more important during fetal development than during breastfeeding. Moreover, these metals (especially Pb) are frequently higher in infant formulas which do not carry the nutritional and psychological advantages and protection of breastfeeding. Infant's reference dose is lower for Hg than for Pb, but risk of Pb contamination for fetuses and infant (breast- or formula-fed) is higher and lasts longer than Hg. Breastfeeding is essential to complete infant development. Interruption or suppression of breast-feeding with cow's milk-based formulas is not an option to environmental pollution.

PMID: 16307830


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16307830&query_hl=3&itool=pubmed_DocSum
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 10:06 AM
Response to Reply #48
49. Great research RedOnce
Now, maybe people who are unwilling to get amalgams out (ME!!) should try adding a selenium supplement. BTW, you gotta be careful not to get too much!! Selenium is really high in Brazil nuts, which I love. At one point I was eating one Brazil nut per day, and that is about the amount of selenium to take.

Of course I use that "quacky" applied kinesiology to assess my supplement needs, so I should probably try that on some selenium, or Brazil nuts.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Thu Mar-23-06 10:17 AM
Response to Reply #49
50. I am a Brazil nut fan as well! From what I have read...
you want to be taking 200 to 400 mcg/day. Above that you are at risk for Selenium toxicity.

I have tinnitus and Selenium tabs aggregate it but Brazil nuts work great! Healthier to.
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Thu Mar-23-06 10:37 PM
Response to Reply #45
53. Effects of micronutrients on metal toxicity.

Effects of micronutrients on metal toxicity.


Environ Health Perspect. 1998 Feb;106 Suppl 1:203-16.
Peraza MA, Ayala-Fierro F, Barber DS, Casarez E, Rael LT.

Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson 85721-0207, USA. peraza@toxic.pharm.arizona.edu

There is growing evidence that micronutrient intake has a significant effect on the toxicity and carcinogenesis caused by various chemicals. This paper examines the effect of micronutrient status on the toxicity of four nonessential metals: cadmium, lead, mercury, and arsenic. Unfortunately, few studies have directly examined the effect of dietary deficiency or supplementation on metal toxicity. More commonly, the effect of dietary alteration must be deduced from the results of mechanistic studies. We have chosen to separate the effect of micronutrients on toxic metals into three classes: interaction between essential micronutrients and toxic metals during uptake, binding, and excretion; influence of micronutrients on the metabolism of toxic metals; and effect of micronutrients on secondary toxic effects of metals. Based on data from mechanistic studies, the ability of micronutrients to modulate the toxicity of metals is indisputable. Micronutrients interact with toxic metals at several points in the body: absorption and excretion of toxic metals; transport of metals in the body; binding to target proteins; metabolism and sequestration of toxic metals; and finally, in secondary mechanisms of toxicity such as oxidative stress. Therefore, people eating a diet deficient in micronutrients will be predisposed to toxicity from nonessential metals.

Publication Types:
Review

PMID: 9539014

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9539014&query_hl=9&itool=pubmed_DocSum




Zinc Status May Play A Role:


Arch Environ Health. 2002 Mar-Apr;57(2):98-102.
Nephrotoxic actions of low-dose mercury in mice: protection by zinc.

Afonne OJ, Orisakwe OE, Obi E, Dioka CE, Ndubuka GI.

Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University, Nwewi Campus, Nigeria. connice@infoweb.abs.net

The authors conducted this study to determine if very-low-dose (i.e., 4 ppm) mercury is nephrotoxic and, if so, whether the nephrotoxic actions of mercury in mice could be prevented by zinc intake. Animals were administered 4 ppm mercuric chloride and/or 800 ppm zinc chloride in their drinking water for 12 wk. The animals were sacrificed at the end of the exposure period, and their kidneys were excised, weighed, and processed for histological study. Both metals reduced significantly (p < .05) the absolute and relative kidney weights of the animals. Zinc-treated animals showed normal kidney histology that was comparable with that of the control. Mercury treatment produced necrosis and widening of the glomeruli, whereas a combination of both metals resulted in protection from the toxic effects, with most nephrons resembling the control. The results indicate that low-dose mercury exposure in mice kidney induces some degenerative effects, which are prevented by zinc.

PMID: 12194165

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12194165&query_hl=9&itool=pubmed_DocSum



Low-dose mercury induces testicular damage protected by zinc in mice.

Eur J Obstet Gynecol Reprod Biol. 2001 Mar;95(1):92-6.

Orisakwe OE, Afonne OJ, Nwobodo E, Asomugha L, Dioka CE.

Department of Pharmacology, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, P.M.B. 5001, Nnewi, Anambra State Nigeria. connice@infoweb.abs.net

OBJECTIVES: This investigation was set out to determine whether mercury at a very low dose (4ppm) induces testicular damage on murine testis, and if so whether the toxic effects of mercury could be prevented by zinc. STUDY DESIGN: One of the following solutions was administered in the drinking water of CD-1 male mice: (1) 4ppm HgCl(2); (2) 800ppm ZnCl(2); (3) 4ppm HgCl(2)+800ppm ZnCl(2); or (4) deionised water; for 12 weeks. At the expiration of the treatment period, animals were sacrificed, testes excised and weighed, and epididymal sperm number taken. The testes were processed for histological examination. RESULTS: Both zinc and mercury significantly (p<0.05) decreased the absolute and relative testicular weights, with mercury producing the highest reduction in weight. Mercury reduced significantly (p<0.05) the epididymal sperm number, while zinc and mercury/zinc produced statistically same effect with control on the sperm number. Histological study showed that mercury at the concentration employed produced remarkable degenerative lesions on the testes, as the zinc-treated group showed a normal morphology. Majority of the animals in the mercury/zinc-treated group exhibited complete or partial protection as evidenced by the morphology of the seminiferous tubules. CONCLUSION: Zinc prevents mercury-induced testicular damage in mouse. These findings highlight the risks exposure to inorganic mercury might pose to male reproduction of mice, and suggests possible therapy with zinc. Study in humans is therefore advocated.

PMID: 11267727

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11267727&query_hl=9&itool=pubmed_DocSum
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Mar-22-06 08:36 AM
Response to Reply #34
40. Multiple anecdotes are not data, philb.
No matter how much you wish they were.

What if I got three people who swore their athlete's foot cleared up once they drank Pepsi? Would you believe that Pepsi was a cure for athlete's foot? Why not?
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RedOnce Donating Member (519 posts) Send PM | Profile | Ignore Wed Mar-22-06 09:03 AM
Response to Reply #40
41. You're right "anecdotes are not data" but what do you make of...
these reports? Why would people go through the expense and inconvenience of amalgam replacement and them take the time to write up their results? Do you think that their positive results are imagined?

I am a newbie to this topic. Has a before/after study ever been done?
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Mar-22-06 09:23 AM
Response to Reply #41
42. I think people can be honestly confused.
They're looking for an easy solution. A quick fix. Someone to blame.

It's comforting, in a way, to be able to point a finger at "big pharma" or other large organizations and feel that they're causing all your problems. It's not you, it's not your lifestyle choices, it's someone else who wants to poison you, for profit.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 12:27 AM
Response to Reply #42
44. Thousands of studies and hundreds of peer-reviewed studies showing
that the majority of those treated aren't simply anecdotes; the science is overwhelming; the mechanisms of causality are documented in the medical literature; the majority of experienced experts are in agreement on this;
the experience of clinics treating large numbers of patients all over the world is consistent. The millions of medical lab tests are consistent.
If you do the tests, determine whats causing the problem and treat the cause, the condition gets better.
Our organization has been interacting with thousands of patients and the clinics treating such for years,
and the results are predictable- most have significant health improvements after amalgam replacement and detox if
done properly for large numbers of conditions. Its documented in the medical literature- peer-reviewed studies of
many thousands of patients, and the experience of those interacting with us is likewise. Consistent and predictible
if they do the right tests and treatments, most improve. http://www.home.earthlink.net/~berniew1/hgremove.html etc. etc.
I've posted URLs of hundreds of peer-reviewed studies with thousands of recoveries; I've posted case histories of 100s of recoveries of people I've interacted with personally.


It should be clear this is real; and even the majority of dentists in modern countries now know it.
And those that don't and still use amalgam, most are documented to have high levels of occupational exposure
and more neurological and immune and reproductive problems.
http://www.home.earthlink.net/~berniew1/dental.html
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 10:44 AM
Response to Reply #44
51. Spare me, philb.
Let me know when the MS Society agrees with your "thousands of studies."

Because right now, they say you're wrong.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-23-06 08:08 AM
Response to Reply #40
47. NIH NHANES III epidemeological study had 35,000 population- not anecdotal
NHanesIII Condition Graphs http://www.vimy-dentistry.com/nhanesgraphs.htm
NHANES III Screening – 35,000 Americans


(Conditions with incidence highly correlated to number of amalgam fillings)
Fewer of those with this condition have zero fillings than those of the general population while more of those with the condition have 17 or more surfaces than in the general population

Infectious and parasitic diseases (001-139)
Cancer (140-239)
Disorders of thyroid gland (240-246)
Mental disorders (290-319)
Diseases of the nervous system and sense organs (320-389)

Other disorders of the central nervous system(MS) (340-349)


Likewise the German study at Tubengin University had 20,000 population tested

Dr. P.Kraub & M.Deyhle, Universitat Tubingen- Institut fur Organische Chemie, “Field Study on the Mercury Content of Saliva”, 1997 ; (tests at Tuebingen Univ. Health Clinic of over 20,000 people, amount of mercury in saliva increased on average approx. 1.5 micrograms per day per amalgam filling; 10% had mercury level greater than 100 micrograms; higher mercury levels were correlated with more chronic health conditions) www.xs4all.nl/~stgvisie/AMALGAM/EN/SCIENCE/tubingen.html


Some of the clinics have treated over 5,000 patients over a period of years who recovered after amalgam replacement and documented it- with records

(35) (a)Huggins HA, Levy,TE, Uniformed Consent: the hidden dangers in dental care, 1999, Hampton Roads Publishing Company Inc; & (b) Hal Huggins, Its All in Your Head, 1997; & (c) Huggins, HA, Solving the MS Mystery: Help, hope and recovery, 2002; &(d) Toxic Elements Research Foundation, Colorado Springs Colorado, “Survery of 1320 patients being treated for heavy metal toxicity”, 2001. 800-331-2303; &
(e)Center for Progressive Medicine, 1999, http://www.hugnet.com


(222) M. Daunderer, Handbuch der Amalgamvergiftung, Ecomed Verlag, Landsberg 1998, ISBN 3 609 71750 5 (in German); & “Improvement of Nerve and Immunological Damages after Amalgam Removal”, Amer. J. Of Probiotic Dentistry and Medicine, Jan 1991; & Toxicologische erfahrungen am menchen; Quecksilber in der umwelf-hearing zum amalgamproblem”,Niedersachsiscles Umweltministerium, 1991; & “Amalgam”, Ecomed-Verlag, Landsberg, 1995; & “Amalgamtest”, Forum Prakt.Allgen.Arzt, 1990, 29(8): 213-4; & “Besserung von Nerven- und Immunschaden nach Amalgamsanierung”,Dtsch.Aschr. F. Biologische Zahnmedzin, 1990, 6(4):152-7. ( amalgam removal & DMPS, over 5,000 cases)

(12) Dimaval Scientific monograph, sixth Ed., Jan 1997, Dr Johann Ruprecht, Heyl Corporation, over 10,000 cases of recovery

http://www.home.earthlink.net/~berniew1/hgrecov.html

many thousands of cases of recovery from Oral Lichen Planus(autoimmune condition with consensus that amalgam is main cause)
http://www.home.earthlink.net/~berniew1/periodon.html

and many thousands of other such cases of recovery or signif. improvement that have been documented
http://www.home.earthlink.net/~berniew1/hgremove.html

and the thousands that myself and DAMS coordinators have interacted with and have some records on
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Kailassa Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Apr-01-06 12:56 AM
Response to Original message
54. Getting my mercury fillings removed did not turn out as expected;
My teeth were all full of fillings, because, as a baby, I was left lying in a cot with a bottle of condensed milk to suck on, and my hands tied to the side-bars. I learned what had been done to me when my misguided mother tried to make me do the same to my own daughter.

It took till I was 40 to save the money to get them all replaced, which I was hoping would help with chronic fatigue. The new white fillings only lasted a year, and when they fell out, my teeth crumbled and I had to have them all pulled out. I felt the chronic fatigue was helped, but the big change I had was not one I had looked for at all.

I had always had a tendancy to go into rages that were terribly hard to control, and would last all day. Being a single mother, I'd had to learn tactics to keep the kids safe from me at those times, but sometimes the best I could do was lock myself in the bathroom for the day. I had tried to get psychiatric help, but psychs would simply act as though they were not hearing what I was saying, or they'd tell me I was just being "bad" and had to stop it.

Since I've had the amalgum out, I've never had another of those rages.

I'm fully aware that one account is not proof of anything, I'm just posting it here because it was an enormous improvement to my life, and, if the amalgum had anything to do with those tempers, that would be worth looking into.
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philb Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-02-06 12:54 AM
Response to Reply #54
55. It makes a big difference who does the work; sounds like you didn't
find a wonderful option.
Its documented in the medical literature that the amount of mercury exposure you get depends on the equipment, training,
and protocol of the dentist you use; and that there is as much as 90% difference in the amount of mercury exposure
(mercury measured in blood,etc.) depending on the dentist that you use.

Also there is a huge difference in how well composite fillings or inlays/onlays or crowns are done and how long they last, depending on the materials used, the dentists skills, etc.

In general other options should last longer than amalgams if properly done. But to do amalgams they often have to cut the tooth deep to stabilize the filling in place, and big amalgams tend to crack the tooth over time requiring crowns; and also are hard to remove without damaging the nerve- which can mean losing the tooth.

But if you get amalgam replaced properly, the dayly level of mercury exposure declines hugely- 80 to 90%
and health generally improves, as has been documented in over 60,000 clinical cases we have records on. Including
a lot that we've interacted with considerably.
http://www.home.earthlink.net/~berniew1/hgremove.html

Mercury also commonly causes anger, rage, depression, agression, suicidal thoughts, etc. as is well documented in the medical literature:
http://www.home.earthlink.net/`berniew1/depress.html
http://www.home.earthlink.net/~berniew1/damspr4.html
http://www.home.earthlink.net/~berniew1/violence.html
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trotsky Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-02-06 04:00 AM
Response to Reply #55
56. It makes a big difference? Why?
If the mercury is out, it's out. EVERYONE who has their amalgam fillings should find all their diseases completely cured, according to you. What difference does it make HOW they came out?

Your studies are all anecdotes or self-referential junk from proven quacks. The very societies that know EVERYTHING about a particular disease completely disagree with your claims. I only hope that no one on DU takes risks with their health because of you.
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Kailassa Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-02-06 08:05 AM
Response to Reply #55
57. Thanks for the info.
I think much of the problem was that I'd always had soft teeth anyway, and had more filling than tooth, so there was not a lot for him to work with.

But I feel so different without it that it was better to end up having to put up with false teeth than having all that metal in my mouth any longer.
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