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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Jun-20-06 08:45 AM
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Vitamin C: Cancer cure?
http://www.philly.com/mld/inquirer/living/health/14842932.htm

This is an absolutely fascinating article. I recommend the whole thing.

The distinction between oral and intravenous is crucial. The body automatically gets rid of extra C through urine. Levine's lab has shown that, at high concentrations, the vitamin is toxic to many types of cancer cells in lab dishes. But to get that much C into the body before it's eliminated, it must be put directly into the blood.

This may explain the defining setback of Pauling's crusade. He and his collaborator, Scottish surgeon Ewan Cameron, gave C intravenously and orally, and claimed many of their cancer patients lived surprisingly long and well. In the 1970s, two rigorous government studies intended to test their claims gave only pills - and found no benefits.

How could so many smart people, including Pauling, ignore a variable as basic as the body's ability to absorb and clear a drug?

"I don't want to impugn anyone," Levine said. "It's one of these things where somebody didn't ask the right questions."


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Redstone Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Jun-20-06 08:53 AM
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1. Whoa, I'm glad I read the whole thing. It's NOT Pauling-type nuttiness
at all. Definitely in the "can't hurt to try it" category.

Redstone
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lindisfarne Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Jun-21-06 02:51 AM
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2. Someone at the National Cancer Institute does seem open to the idea
so that's promising. The fact that it may not have stirred up much interest may reflect the fact that few scientists in cancer research have much expertise in intravenous Vitamin administration. But the article does say that some small trials with private funding are in the works - if they have promising results, federal funding should be the next step.

"Jeffrey White, director of the National Cancer Institute's office of cancer complementary and alternative medicine, said that he's tried to "generate awareness" of Levine's research, and believes it justifies more studies in humans. But White acknowledged that the NCI has rejected "a few" proposals for such studies."

Armed with this new evidence, a coterie of researchers - all associated with Pauling or his disciples - have recently obtained private funding for small trials of intravenous C.

University of Kansas Medical Center physician Jeanne Drisko has $375,000 for a trial of 30 ovarian cancer patients. In Montreal, McGill University oncologist Wilson Miller has $300,000 to find the maximum safe doses for treating various cancers.


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